ABSTRACT
Progressive massive fibrosis (PMF) involves extensive fibrosis of the lung and is usually bilateral in nature. This lesion occurs in patients showing silicosis and other pneumoconioses, including asbestosis, coal workers' pneumoconiosis, or mixed dust fibrosis. PMF tends to exacerbate fairly rapidly and may continue to grow even if the dust hazard is removed. It is frequently associated with functional impairment, including reduction in lung compliance, lung volumes, diffusing capacity, and presence of hypoxemia. However, pulmonary hemorrhage is rarely observed along with PMF. We present an autopsy case of a silicosis patient who died as a result of PMF complicated with massive hemoptysis.
Subject(s)
Humans , Hypoxia , Asbestosis , Autopsy , Coal , Dust , Fibrosis , Hemoptysis , Hemorrhage , Lung , Lung Compliance , Pneumoconiosis , SilicosisABSTRACT
The stercoral colitis is an inflammatory process involving the colonic wall related to fecal impaction. This rare condition usually has a poor prognosis. We experienced a death case where an 84 years old woman died of stercoral colitis complications after total knee arthroplasty surgery. The fatal complications were peritonitis with systemic inflammatory response syndrome, not accompanying bowel perforations. We would like to show the autopsy case of stercoral colitis and suggest the importance of early suspicion and treatment.
Subject(s)
Female , Humans , Arthroplasty , Autopsy , Colitis , Colon , Fecal Impaction , Knee , Peritonitis , Prognosis , Systemic Inflammatory Response SyndromeABSTRACT
Coronary artery fistula (CAF) is a rare congenital malformation, comprising less than 1% of all congenital heart disease. Most fistulas drain into the right-sided heart chambers or pulmonary artery, and termination in left heart chambers is an uncommon finding. Clinical presentation mainly depends on the severity of the left-to-right shunt, and adult patients usually do not develop any symptom. There are few case reports relating CAF manifested as an exceptional form of sudden unexpected death. We experienced a case of a 62-year-old male with a single CAF arising from left main coronary artery which drains into the left ventricle, and reported with review of the related articles.
Subject(s)
Adult , Humans , Male , Middle Aged , Cardiomegaly , Coronary Vessels , Death, Sudden , Fistula , Heart , Heart Diseases , Heart Ventricles , Pulmonary ArteryABSTRACT
BACKGROUND: This study was performed to ascertain the usefulness of the human papillomavirus (HPV) DNA microchip test for the screening and management of women with atypical squamous cells of undetermined significance (ASC-US). METHODS: The subject group consisted of 534 patients, and all of whom were diagnosed as ASC-US according to a Papanicolaou smear, and they all underwent concomitant HPV DNA microchip test. RESULTS: The occurrence rates of overall squamous lesions and high risk lesion (cervical intraepithelial neoplasia grade 2 and grade 3, and invasive carcinoma) of the HPV-positive ASC-US patients were significantly higher than those of the HPV-negative ASC-US patients. High risk lesion was detected more frequently among the older patients and the patients with HPV 56, 33 or 70. On the follow-up HPV DNA microchip test, only 1 of 11 (9.1%) HPV type-switched women developed squamous lesion compared with 8 of 13 (61.6%) HPV type-persistent women who developed squamous lesion. CONCLUSIONS: The HPV DNA microchip test is useful for the management of ASC-US patients. HPV-positive ASC-US patients should undergo a HPV DNA microchip test periodically. If the same genotype of HPV is persistent on the follow-up test, more increased surveillance is needed.
Subject(s)
Female , Humans , DNA , Follow-Up Studies , Genotype , Mass Screening , Oligonucleotide Array Sequence Analysis , Vaginal SmearsABSTRACT
Ectopic liver is a rare entity that has been previously identified during abdominal exploration for other surgery and this has usually been described in the vicinity of the liver such as on the gallbladder, hepatic ligaments, diaphragm, thoracic cavity, adrenal glands, pancreas, omentum, spleen, esophagus and umbilical cord. Most cases of ectopic liver reported in the literature were located in the gallbladder. We report here on a case of ectopic liver related to the gallbladder, and this was encountered during an elective laparoscopic cholecystectomy.